Summary
The Witcher 3is one of the best video games ever made, filled to the brim with content spread across a beautiful open world along with a cast of amazing characters that have become a legendary part of video game culture in their own right. From everyone’s favorite protagonist in the form of Geralt, all the way to the rebellious spirit of Cirilla —The Witcher 3’s impact on gaming as a whole is quite apparent.
Several gameplay mechanics inThe Witcher 3can be utilized for a whole host of benefits, but one particular avenue that a lot of players don’t check out is that of alchemy. Sure, making potions and decoctions might be useful, but most players feel that there’s enough loot present in the open world to rely on instead of wading through more menus. However, some of thebestWitcher 3decoctionsthat Geralt can brew are helpful and more than useful enough to justify using alchemy.
Updated on July 31, 2025, by Ritwik Mitra:The Witcher 3 features many gameplay pillars that players can ignore at lower difficulties, but it’s important to use every advantage Geralt can enjoy at higher difficulties to ensure that he can come out victorious againstthe toughest foes in the game. Oils, potions, Signs, and the best swords around do a great job of letting the White Wolf destroy his foes in style, and one of the best ways to buff Geralt is to use thebest Witcher 3 decoctionsthat can be concocted after defeating some tough monsters.
18Wyvern Decoction
Consecutive Attacks Bolster Attack Power
DPS is one of the biggest things thatWitcher 3players must control if they want to take out enemies quickly without incurring too much damage. With certain potions, players can buff themselves up and enhance their attack power to destroy their foes in no time. This includes the wyvern decoction, a useful potion that players can use if they want to launch a series of light attacks against their opponents.
It’s one of thebestWitcher 3decoctionsthat players can use if they want to pile on the damage against numerous foes. This potion is especially effective if players are confident in their skills and are dealing against enemies that dodge strong attacks, letting them use light attacks to land quick hits while enhancing the damage of each strike.
17Wraith Decoction
A Quen Shield Auto Activates After A Hit Depletes One-Third Of Geralt’s Vitality
Quen is one of themost useful Signs inThe Witcher 3, letting Geralt tank certain blows with ease and unleash a sustained offense on his opponents with no issues. However, remembering to cast this spell after the protection ward is dispelled is easier said than done, with the frenetic nature of the combat leading to players finding it harder to keep track of so many things at once. This is a problem that rears its head at higher difficulties and needs to be remedied.
With one of thebestWitcher 3decoctions, players can easily set up an auto-Quen whenever they’re hit with a major blow. The help provided by this decoction can’t be highlighted enough, especially since most tough enemies can inflict a ton of damage on Geralt with a single hit. This makes it important to imbibe this decoction and turn the tide of battle against their foes, negating their attacks at a time when players are unaware of their dire situation and may be taken out with a fatal hit.
16Reliever’s Decoction
Become More Effective While Fighting Wraiths
Wraiths are some of the toughest enemies inThe Witcher 3. These corporeal enemies are a pain to damage, and players must ensure that they’re casting Yrden regularly to ensure that their sword strikes do enough damage instead of just passing through them harmlessly. Maintaining this spell all the time is a nightmare for fans, which is why players would love one of thebestWitcher 3decoctionsthat take care of this headache for them.
Not only does the reliever’s decoction enhance Geralt’s damage and defense against these foes, but it also ensures that these enemies don’t need to be trapped with Yrden all the time to leave them susceptible to damage. Players should keep in mind that the initial cast of Yrden is still necessary to capture these wraiths, but that’s the only time gamers will need to place this magical hex if they’re bolstered by the effects of this potion.
15Arachas Decoction
More Weight Carried And Heavier Armor Leads To The Player Taking Less Damage (Despite The In-Game Description Stating Otherwise)
The Arachas are some of the toughest enemies inThe Witcher 3, and most players ignore the decoction formed by these monsters because they don’t wear light armor. So, players will be delighted to know that there’s a mistake in this description.
TheArachas decoctionincreases the player’s damagebased on the weight they carry, which is the complete opposite of what is stated in the game text. This blooper may make players think that the Arachas decoction is a waste of resources when it’s anything but.
14Leshen Decoction
A Portion Of The Damage Dealt By Enemies Is Reflected Back At The Attacker
Leshens are powerful monsters who need to be defeated using a combination of Signs and strong attacks. TheLeshen decoctionthat players can create from its mutagen is pretty useful and does a great job of turning an enemy’s attack against them.
Of course, players whose main priority is to avoid damage altogether may find this decoction to be somewhat counter-productive. Still, this shouldn’t take away from the sheer enjoyment gamers can enjoy from watching an enemy perish at the hands of their own attack, courtesy of this decoction.
13Alghoul Decoction
Adrenaline Points Are Generated 50% Faster Than Normal Until The First Successful Enemy Attack
Adrenaline is a vital resource that players need to generate in battle time and time again if they wish to enjoy the benefits of higher damage values while also unleashing powerful moves of their own. Initially, these points are generated rather slowly in battle, but there are ways in which players can hasten this recovery rate.
For starters, theAlghoul decoctionincreases the generation of Adrenaline Points by 50%, but players have to be mindful to avoid damage as much as possible. Given how wonky the hitboxes of the game are, it’s easy to see why this decoction can be quite tricky to make the most use of during a hectic battle with numerous enemies.
12Chort Decoction
Provides Complete Resistance To Stagger, And Knockdown Effect Is Reduced To Stagger
A Chort is a huge and powerful enemy that cow-killers inThe Witcher 3will be intimately familiar with. This foe is no slouch to beat, but undertaking these battles is worth it simply because of the decoction that players can brew afterward.
Being staggered is one of the most annoying parts ofThe Witcher 3, and this decoction completely negates this effect. Players can simply tank through attacks and land powerful combos that will slice and dice the toughest foes without too many issues.
11Archgriffin Decoction
Strong Attacks Consume Stamina And Reduce The Struck Foe’s Vitality For An Additional 5%
The Archgriffin is a fearsome foe, and not many of them can be encountered in the game. Players who fight against these winged beasts need to be careful of their every move, especially since Geralt’s health bar can be shredded to ribbons if one isn’t careful enough. Defeating this enemy is worthwhile simply because of the decoction that can be obtained after defeating them.
TheArchgriffin decoctionis the perfect alchemical solution that players will need duringthe two tough-as-nails DLCs. BothHearts of StoneandBlood & Wineup the challenge to the max, making it important for players to use this potion to enhance their damage output against the many enemies in this expansion who can genuinely feel like health sponges. Using this decoction against bosses is also a great way to increase Geralt’s DPS, but players should be aware of the fact that this increase in damage comes at the cost of Geralt’s stamina being depleted with each strong attack.
10Ekhidna Decoction
Performing Actions That Consume Stamina Regenerates Vitality
Stamina is another thing that players need to keep an eye out for during combat inThe Witcher 3. Signs, blocking, and sprinting are all governed by it, and players can use this mechanic to aid them with theEkhidna decoction.
After getting a mutagen from this enemy, Geralt can brewa potion that restores healthwhenever he expends Stamina. Casting Signs and restoring health at the same time is a pretty substantial bonus, especially against tough opponents who can only be left vulnerable with magic.
9Ancient Leshen Decoction
Each Sign Cast Increases Stamina Regeneration For The Remainder Of The Fight
Players who cast Signs frequently in combat will be more than appeased with what theAncient Leshen decoctionachieves. It enhances Stamina Regeneration with each Sign cast, allowing players to decimate their foes with a flurry of blows and magic.
Players who use up a lot of Stamina with the many special moves in the game will be well-serviced by this decoction. It’s a great way to minimize the Stamina loss from spells and let players diversify the wealth of combat actions they can perform in an encounter.
